Pompholyx is also called dishydrotic eczema. This appears as intensely itchy vesicles on the hands, fingers and soles of the feet. The cause of this pattern of eczema is not fully understood but in some cases there is a history of allergic contact dermatitis especially to nickel. Very often no specific allergen is found despite extensive patch testing. This form of eczema is aggravated by stress. Oral antihistamines help to alleviate the intense itch. Frequently applied calamine lotion helps to cool the affected skin.