Medical Q&As

Gilbert's syndrome?

I have been told that I have Gilbertís Syndrome. There are times when I feel really tired. Does Gilbertís Syndrome cause this?

Gilbertís syndrome is a benign but chronic condition resulting in raised levels of bilirubin in the blood. Bilirubin is produced in the liver and an elevated level of this chemical causes jaundice. The jaundice tends to fluctuate and people are often unaware of it until it is noticed by their doctor or perhaps the raised bilirubin is detected during routine blood testing. Prolonged fasting, excessive exertion, alcohol consumption, an infectious illness and surgery exacerbate the jaundice. The functions of the liver are not affected and liver biopsy does not reveal any abnormal changes in the architecture of the liver. You question if fatigue is a feature of the condition. This may be a case of putting the cart before the horse because fatigue usually exacerbates the jaundice and not the other way round. Essentially Gilbertís syndrome is a benign medical curiosity without symptoms other than jaundice. Your fatigue may be related to over exertion or other factors not related to Gilbertís syndrome.