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Gene link diabetes discovery

[Posted: Mon 13/08/2012]

A new scientific discovery on the genetics of diabetes may improve our understanding of the condition.

UK researchers have discovered 10 genetic 'hotspots' that are linked to the development of type 2 diabetes.

They were probing how some people may have more of a genetic predisposition to diabetes than others.

The researchers now say their discovery of 10 gene regions shown to be linked to diabetes will improve our understanding of the disease.

This in turn will help the development of new drug treatments for the condition, which is set to reach epidemic levels in Ireland in the coming years.

Around 90% of people with diabetes have the type 2 version of the condition, which is linked to obesity and lifestyle factors.

The researchers examined DNA from almost 35,000 people with Type 2 and 115,000 healthy people. They identified 10 new areas where genetic changes could be linked to a person being at risk of getting the disease.

The research, carried out at the Wellcome Trust Centre for Human Genetics at Oxford, is published in the journal Nature Genetics.




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